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A laboratory at the Forsyth Institute,

Boston, MA

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PUBLICATIONS

Julia Downes, Sonia Vartoukian, Floyd E. Dewhirst, Jacques Izard, Tsute Chen, Wenhan Yu, Iain C. Sutcliffe and William G. Wade.
Pyramidobacter pisciolens gen. nov., sp. nov., a member of the phylum ‘Synergistetes’ isolated from the human oral cavity.
International Journal of Systematic and Evolutionary Microbiology (2009) vol. 59 pp. 972-980.
DOI 10.1099/ijs.0.000364-0.
[Text as a pdf file] [Table S1] [Table S2] [Table S3] [Table S4]

Jacques Izard*, Chyong-Ere Hsieh, Ronald J. Limberger, Carmen A. Mannella and Mike Marko.
Native cellular architecture of Treponema denticola revealed by cryo-electron tomography.
Journal of Structural Biology (2008). Vol.163 (1) pp. 10-17.
[ text pdf file] [Supplemental Figures and Table] [Movie S1] [Movie S2] [Movie S3] [abstract]

Jacques Izard*.
Cytoskeletal cytoplasmic filament ribbon of Treponema: a member of an intermediate-like filament protein family.
Journal of Molecular Microbiology and Biotechnology (2006). Vol. 11 pp. 159-166.
[text as a pdf file]

Federico Foschi, Jacques Izard, Hajime Sasaki, Victorio Sambri, Carlo Prati, Ralph Müller, and Philip Stashenko.
Treponema denticola in disseminating endodontic infections. (Cover)
Journal of Dental Research (2006). vol. 85 (8) pp.761-765.
[text as a pdf file]

Jacques Izard, and Ronald J. Limberger.
Structural and genomic features of treponemal architecture.
Book Chapter in: Treponema molecular and cellular biology.
J. Radolf and S.A. Lukehart (ed.) Horizon Bioscience (2006). ISBN 1-904455-10-7.
[text as a pdf file]

Anne C. R. Tanner and Jacques Izard.
Tannerella forsythia, a periodontal pathogen entering the genomic era.
Periodontology 2000 (2006). vol. 42 pp. 88-113.
[text as a pdf file]

Jacques Izard*, Chyongere-E. Hsieh, Carmen A. Mannella, Ronald J. Limberger, and Mike Marko.
Periplasm organization in Treponema denticola as studied by cryo-electron tomography.
Microscopy and Microanalysis (2005) vol. 11 (Suppl 2) pp340-341.
[text as a pdf file]

Anne C. R. Tanner and Jacques Izard.
Etiology of oral disease in view of microbial complexity.
Oral Biosciences & Medicine (2005) vol.2 n. 2/3 pp. 209-213.
[text as a pdf file]

Linda Slivienski-Gebhardt, Jacques Izard, William A. Samsonoff, and Ronald J. Limberger.
Development of a novel chloramphenicol-resistance expression plasmid used for genetic complementation of a fliG-deletion mutant of Treponema denticola.
Infection Immunity (2004), vol. 72(9) pp. 5493-5497.
[text as a pdf file]

Jacques Izard*, Bruce F. McEwen, Rita M. Barnard, Thomas Portuese, and Ronald J. Limberger.
Tomographic reconstruction of treponemal cytoplasmic filaments reveals novel bridging and anchoring components.
Molecular Microbiology.(2004) vol. 51 (3) pp. 609-618.
[text as a pdf file] [extra material (movie)]

Jacques Izard*, and Ronald J. Limberger.
Rapid Screening Method for Quantitation of Bacterial Lipids from Whole Cells.
Doi: 10.1016/S0167-7012(03)00193-3
Journal of Microbiological Methods. (2003) vol. 55 n. 2, pp. 411-418.
[text as a pdf file]

Jacques Izard* and Ronald J. Limberger.
Pleiotropic Defects in a Treponema denticola Cytoplasmic Filament Mutant.
Journal of Bacteriology (2001) vol. 183 n. 3 pp. 1078-1084.
[text as a pdf file]

Jacques Izard*, William. A. Samsonoff, Mary-Beth Coy and Ronald J. Limberger.
Genetic and Structural Analysis of the Cytoplasmic Filaments of Wild-type and a Flagella Filament-deficient Isolate of Treponema phagedenis.
Journal of Bacteriology (1999) vol. 181 n. 21 pp. 6739-6746.
[text as a pdf file]

Ronald J. Limberger, Linda L. Slivienski, Jacques Izard and William A. Samsonoff.
Insertional Inactivation of Treponema denticola tap1 Results in a Non-Motile Mutant with Elongated Flagellar Hooks.
Journal of Bacteriology (1999) vol. 181 n. 12 pp. 3743-3750.
[text as a pdf file]

Denis Duché, Jacques Izard, Juan M. Gonzalez-Mañas, Michael W. Parker, Martine Chartier and Daniel Baty.
Two Disulfide Bonds Introduced in the Colicin A Pore-forming Domain Block the in vivo but not the in vitro Toxin Activity.
Journal of Biological Chemistry (1996) vol. 271 n°26, pp. 15401-15406.
[text as a pdf file] [abstract]

Rita Vos and Yves Engelborghs; Jacques Izard and Daniel Baty.
Fluorescence Study of the Three Tryptophan Residues of the Pore-forming Domain of Colicin A Using Multifrequency Phase Fluorometry.
Biochemistry (1995) vol. 34, pp. 1734-1743..
[text as a pdf file]

Jacques Izard, Michael W. Parker, Martine Chartier, Denis Duché and Daniel Baty. A Single Amino Acid Substitution Can Restore the Solubility of Aggregated Colicin A Mutants in Escherichia coli.
Protein Engineering (1994) vol. 7 n°12, pp. 1495-1500.
[text as a pdf file]
[Protein Engineering has been relauched in 2004 as Protein Engineering, Design and Selection]